Activated platelet profile and albuminuria Correlation between albuminuria and spontaneous platelet micro-aggregate formation in type 2 diabetic patients Running title: Activated platelet profile and albuminuria

نویسندگان

  • Shin-ichi Araki
  • Hiroyuki Matsuno
  • PHD
  • Masakazu Haneda
  • Daisuke Koya
  • Yosuke Kanno
  • Junko Itho
  • Akio Kishi
  • Keiji Isshiki
  • Toshiro Sugimoto
  • Hiroshi Maegawa
  • Atsunori Kashiwagi
  • Takashi Uzu
چکیده

From the Department of Medicine, Shiga University of Medical Science, Otsu, Shiga, Japan; Department of Clinical Pathological Biochemistry, Doshisha Women’s Collage Liberal Arts, Kyotanabe, Kyoto; Division of Metabolism and Biosystemic Science, Department of Medicine, Asahikawa Medical College, Asahikawa, Hokkaido, Japan; and Division of Endocrinology & Metabolism, Department of Medicine, Kanazawa Medical University, Kahoku-gun, Ishikawa, Japan.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Correlation Between Albuminuria and Spontaneous Platelet Microaggregate Formation in Type 2 Diabetic Patients

OBJECTIVE Albuminuria in type 2 diabetic patients is a risk factor for cardiovascular disease. We investigated the correlation between albuminuria and spontaneous microaggregation of platelets (SMAP) formed under shear stress. RESEARCH DESIGN AND METHODS The study subjects were 401 type 2 diabetic individuals (252 with normoalbuminuria and 149 with albuminuria) who were examined for SMAP unde...

متن کامل

Oxidized LDL is Correlated with Urine Albumin in Type 2 Diabetes Mellitus: A Case-Control Study

Objective: In patients with diabetes mellitus, increased rate of lipoprotein oxidation and oxidative stress have important role in diabetic angiopathy, including nephropathy. We designed a study for comparing the level of Ox-LDL in diabetic patients with Macro-albuminuria, Micro-albuminuria, versus Normo-albuminuric. Materials and Methods: One hundred and thirty five patients with type 2 dia...

متن کامل

The Effect of Selenium on Micro-Albuminuria in Diabetic Patients: A Randomized Clinical Trial

Objective: Oxidative stress plays an important role in the onset and progression of diabetic nephropathy. So antioxidant agents may be one of the key treatment strategies for prevention of diabetic nephropathy progression .The aim of this study was to determine the effect of selenium (Se) on micro-albuminuria in type 2 diabetic (T2DM) patients. Materials and Methods: This study was a clinical ...

متن کامل

Microparticle Formation and Platelet Shrinkage in Type-I Glanzmman Thrombasthenia Platelets

Background: Activated normal platelets undergo many biochemical and morphological changes, some of which are apoptotic. Platelet derived microparticles and shrinked platelets as hallmark of platelet activation and apoptosis disperse surfaces containing procoagulant activity around injured vessels and tissues. This study was conducted to determine microparticles formation and platelet shrinkage ...

متن کامل

Effects of additive therapy with spironolactone on albuminuria in diabetes mellitus: A pilot randomized clinical trial

Background: Early diagnosis of albuminuria and the prevention of its progression to macroalbuminuria and diabetic nephropathy are crucial. Angiotensin converting enzyme inhibitors (ACEIs) and antagonists of angiotensin II receptors type I (ARBs) are currently used as first-line treatment for albuminuria in these patients. The present study was conducted to assess the efficacy of addition of spi...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2009